Population
Dogs (normal and with renal artery constriction)
Design
Preclinical
Authors
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Suggests selective antirenin effects in experimental renovascular hypertension; leaves open any clinical translation.
This preclinical study proposes that renin formation is controlled by a pressure-sensitive feedback mechanism between the juxtaglomerular cell and postglomerular resistance.
H. E. Schmid (1962) studied this question.
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