Population
ICR Swiss mice
Comparison
Infection with diabetogenic D or nondiabetogenic… vs Comparison between EMC-D and EMC-B variants
Design
Preclinical
Follow-up
4 days
Authors
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No immediate clinical translation from this murine model; leaves open EMC variant roles in human viral diabetes.
The diabetogenic and nondiabetogenic variants of the EMC virus exhibit different tissue tropisms and distinct effects on pancreatic insulin levels in mice.
Gould et al. (1984) studied this question.
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