Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 1, 1981American Journal of Clinical Pathology

Diagnosis of Acute Hepatitis A by HAVAB®-M, a Direct Radioimmunoassay for IgM Anti-HAV

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does HAVAB-M accurately diagnose acute hepatitis A by detecting IgM anti-HAV?

Population

Sera from patients with hepatitis A, hepatitis B, other infectious diseases, and rheumatoid factor

Design

Other

Authors

RDRichard H. DeckerFulcrum Therapeutics (United States)SKSusan M. KosakowskiAbbott (United States)AVAnne S. VanderbiltCleveland Clinic

Discussion

Loading...

Member takes

Overview

May support early IgM-based diagnosis of acute hepatitis A; leaves open prospective validation in diverse cohorts.

Structured PICO

Does HAVAB-M accurately diagnose acute hepatitis A by detecting IgM anti-HAV?

P
Population
Sera from patients with hepatitis A, hepatitis B, other infectious diseases, and rheumatoid factor
I
Intervention
HAVAB-M (a three-step solid-phase radioimmunoassay for IgM anti-HAV)
O
Outcome
Sensitivity and specificity for IgM antibody to HAVsurrogate

HAVAB-M is a highly sensitive and specific radioimmunoassay for the early diagnosis of acute hepatitis A.

Cite This Study

Decker et al. (1981) studied this question.

synapsesocial.com/papers/6a8cfe9decc95fc4f545dcbfhttps://doi.org/10.1093/ajcp/76.2.140
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A Solid-Phase Radioimmunoassay for Detection of IgM Antibodies to Hepatitis A Virus1979 · 100 citations
  2. 2Serodiagnosis of viral hepatitis A: detection of acute-phase immunoglobulin M anti-hepatitis A virus by radioimmunoassay1977 · 102 citations
  3. 3Serodiagnosis of viral hepatitis A by a modified competitive binding radioimmunoassay for immunoglobulin M anti-hepatitis A virus1979 · 71 citations
  4. 4Evaluation of an immunochromatographic assay for the detection of anti-hepatitis A virus IgM2010 · 13 citations
  5. 5Detection of hepatitis A virus and antibody by solid-phase radioimmunoassay and enzyme-linked immunosorbent assay with monoclonal antibodies1985 · 18 citations