Key result
Nifedipine (20 mg) produced a hypotensive effect in patients with essential hypertension, which was enhanced during normal sodium intake compared to low and high sodium regimens.
Why the study?
Does nifedipine 20 mg oral reduce blood pressure differently under low, normal, or high sodium intake in patients with moderate essential hypertension?
Population
7 patients with moderate essential hypertension
Comparison
Nifedipine 20 mg oral during low, normal, and… vs Comparison between low, normal, and high sodium…
Design
Other
Follow-up
3 hours
Authors
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Nifedipine hypotensive effect may be enhanced by normal sodium intake in essential hypertension; hypothesis-generating for dietary modulation of CCB response.
Does nifedipine 20 mg oral reduce blood pressure differently under low, normal, or high sodium intake in patients with moderate essential hypertension?
Nifedipine induces a hypotensive effect in patients with moderate essential hypertension, which is modulated by sodium intake and most enhanced during a normal sodium diet.
Valdés et al. (1982) studied moderate essential hypertension (n=7). Nifedipine vs. Low and high sodium intakes was evaluated on Blood pressure. Nifedipine (20 mg) produced a hypotensive effect in patients with essential hypertension, which was enhanced during normal sodium intake compared to low and high sodium regimens.
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