Key result
Screening of the AGT gene in 445 individuals identified 5 novel variants potentially contributing to the development of essential hypertension.
Population
215 patients with essential hypertension and 230 normotensive controls
Comparison
Genetic screening of the AGT gene vs Normotensive controls
Design
Case-control
Authors
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Novel AGT variants may extend genetic targets for hypertension research; leaves open any clinical screening or risk-stratification role.
Case-Control (n=445)
The identification of five novel variants in the AGT gene provides new genetic targets for understanding the mechanisms underlying essential hypertension.
Charita et al. (2014) conducted a case-control in Essential hypertension (n=445). AGT gene variants vs. Normotensive controls was evaluated on Detection of novel variants in the AGT gene. Screening of the AGT gene in 445 individuals identified 5 novel variants potentially contributing to the development of essential hypertension.