Why the study?
Does the level of hypothermia and use of circulatory arrest affect cerebral fractional oxygen extraction in children undergoing cardiopulmonary bypass?
Population
30 children undergoing cardiopulmonary bypass
Comparison
Profound hypothermia with total circulatory… vs Mild or moderate hypothermia
Design
Cohort
Follow-up
Postoperatively
Authors
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Circulatory arrest linked to stable cerebral FOE on rewarming; hypothesis-generating for hypoxic injury timing in pediatric bypass.
Does the level of hypothermia and use of circulatory arrest affect cerebral fractional oxygen extraction in children undergoing cardiopulmonary bypass?
In children undergoing cardiopulmonary bypass, circulatory arrest prevents the normal increase in cerebral fractional oxygen extraction seen during rewarming, which may have implications for the timing of hypoxic brain injury.
Wardle et al. (1998) studied this question.
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