Key result
Mass campaigns with oral poliovirus vaccines achieved a >99.5% worldwide reduction in polio cases between 1988 and 2004, raising questions about when and how to stop OPV vaccination.
Design
Review
Authors
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Highlights need for coordinated OPV cessation planning; leaves open optimal timing and strategies for safe global withdrawal.
The paper reviews the historical success of oral poliovirus vaccine in eradicating polio and raises the question of when and how to stop its use.
Hull et al. (2005) conducted a review in Polio. Oral poliovirus vaccine (OPV) vs. Inactivated poliovirus vaccine (IPV) was evaluated. Mass campaigns with oral poliovirus vaccines achieved a >99.5% worldwide reduction in polio cases between 1988 and 2004, raising questions about when and how to stop OPV vaccination.
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