Key result
Long-term antihypertensive therapy reduces cardiovascular events but fails to lower risk to normotensive levels.
Why the study?
Does long-term antihypertensive drug therapy reduce cardiovascular risk to the level of normotensive subjects in hypertensive patients?
Population
Hypertensive patients
Comparison
Antihypertensive pharmacological treatment vs Comparable normotensive subjects
Design
Review
Authors
Loading...
Residual risk persists in treated hypertension; leaves open whether targeting irreversible changes or tighter control further narrows the gap.
Does long-term antihypertensive drug therapy reduce cardiovascular risk to the level of normotensive subjects in hypertensive patients?
Long-term antihypertensive therapy reduces cardiovascular morbidity and mortality, but does not normalize risk to the level of normotensive individuals, possibly due to irreversible changes, drug adverse effects, or inadequate blood pressure control.
L. Hansson (1988) conducted a review in Hypertension. Antihypertensive therapy vs. Normotensive subjects was evaluated. Long-term antihypertensive therapy reduces cardiovascular morbidity and mortality, but fails to lower risks in treated hypertensive patients to the level seen in comparable normotensive subjects.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: