Why the study?
Heart failure is a common clinical feature of advanced cardiovascular disease with high mortality, motivating investigation into its pathogenesis and clinical translation.
A narrative review discussing the pathogenesis of heart failure and the translation of experimental findings to clinical practice.
Answers are grounded in this paper and cite their sources.
Personal narrative on HF pathogenesis translation underscores barriers to clinic; leaves open which experimental insights merit prospective trials.
Heart failure is a common clinical feature of advanced cardiovascular disease that carries a high mortality risk. This review focuses on my journey seeking to understand the pathogenesis of heart failure and on how to translate experimental findings into the clinic.
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Motoaki Sano (2012) conducted a review in Cardiovascular disease and heart failure.
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