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September 5, 2025Open Access

Table S8 from NF1 Loss Promotes EGFR Activation and Confers Sensitivity to EGFR Inhibition in NF1-Mutant Melanoma

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NF1 loss promotes EGFR activation, enhancing potential treatment response in NF1-mutant melanoma.
Gene expression comparisons reveal significant differences between shEGFR and shScramble treatments in melanoma cells.
This assessment involved analyzing differential gene expression data to understand therapeutic responses.
These findings may guide treatment strategies for patients with NF1-mutant melanoma and highlight gene targets.

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Analysis shows NF1 loss increases EGFR activation in melanoma, suggesting potential benefits of EGFR inhibition.

Differential gene expression table shEGFR vs shScramble

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Ibrahim et al. (2025) studied this question.

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Analysis shows NF1 loss increases EGFR activation in melanoma, suggesting potential benefits of EGFR inhibition.

Differential gene expression table shEGFR vs shScramble