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This is a Pathway analysis study.

September 5, 2025Open Access

Table S9 from NF1 Loss Promotes EGFR Activation and Confers Sensitivity to EGFR Inhibition in NF1-Mutant Melanoma

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NF1 loss significantly promotes EGFR activation, ultimately enhancing sensitivity to EGFR inhibition.
The pathway analysis of differentially expressed genes reveals critical mechanisms influenced by EGFR in NF1-mutant melanoma.
Observational analysis of gene expression changes focuses on NF1 and EGFR interactions in melanoma cells.
These findings suggest potential for targeted therapy in NF1-mutant melanoma cases.

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KEGG pathway analysis demonstrates EGFR inhibition impact in NF1-mutant melanoma, suggesting potential therapeutic strategies.

KEGG pathway analysis of DEGs shEGFR vs shScramble

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Ibrahim et al. (2025) studied this question.

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KEGG pathway analysis demonstrates EGFR inhibition impact in NF1-mutant melanoma, suggesting potential therapeutic strategies.

KEGG pathway analysis of DEGs shEGFR vs shScramble