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October 15, 2025Open Access

Figure S7 from SRSF9 Forms Phase-Separated Condensates to Promote Ovarian Cancer Progression by Inducing RNA Alternative Splicing That Is Inhibited by m⁶A Modification

Xinzhao Zuo Jie Xu Dan Yang Chenyue Yang Xiaoyi Liu Ningxuan Chen Haocheng Wang Xin Luo Qingya Luo Yuan Wang Qinglv Wei Yu Yang Hongyan Zhao Jing Xu Wei Wang Tao Liu Ping Yi

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Key Points

SRSF9 enhances ovarian cancer progression by inducing RNA alternative splicing.
Key evidence shows that SRSF9's phase separation activity directly relates to its splicing function.
Analysis employs public tools to predict SRSF9's phase separation potential and its role in cancer.
Findings imply that m6A modification could be targeted for therapeutic strategies against ovarian cancer.

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Implication

Observational analysis reveals SRSF9 promotes RNA alternative splicing in ovarian cancer, indicating m6A modification inhibition.

Abstract

Prediction of SRSF9 phase separation potential by using public tools.

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Cite This Study

Zuo et al. (2025) studied this question.

synapsesocial.com/papers/68f199bfde32064e504dcc59 https://doi.org/10.1158/0008-5472.30363276

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S3 from SRSF9 Forms Phase-Separated Condensates to Promote Ovarian Cancer Progression by Inducing RNA Alternative Splicing That Is Inhibited by m<sup>6</sup>A Modification2025
2Figure S1 from SRSF9 Forms Phase-Separated Condensates to Promote Ovarian Cancer Progression by Inducing RNA Alternative Splicing That Is Inhibited by m<sup>6</sup>A Modification2025
3Figure S5 from SRSF9 Forms Phase-Separated Condensates to Promote Ovarian Cancer Progression by Inducing RNA Alternative Splicing That Is Inhibited by m<sup>6</sup>A Modification2025
4Figure S6 from SRSF9 Forms Phase-Separated Condensates to Promote Ovarian Cancer Progression by Inducing RNA Alternative Splicing That Is Inhibited by m<sup>6</sup>A Modification2025
5Figure S10 from SRSF9 Forms Phase-Separated Condensates to Promote Ovarian Cancer Progression by Inducing RNA Alternative Splicing That Is Inhibited by m<sup>6</sup>A Modification2025