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October 15, 2025

Figure S3 from SRSF9 Forms Phase-Separated Condensates to Promote Ovarian Cancer Progression by Inducing RNA Alternative Splicing That Is Inhibited by m⁶A Modification

Xinzhao Zuo Jie Xu Dan Yang Chenyue Yang Xiaoyi Liu Ningxuan Chen Haocheng Wang Xin Luo Qingya Luo Yuan Wang Qinglv Wei Yu Yang Hongyan Zhao Jing Xu Wei Wang Tao Liu Ping Yi

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Key Points

SRSF9 knockdown reduces ovarian cancer cell growth and metastasis significantly, affecting progression.
The impact of SRSF9 knockdown on epithelial-mesenchymal transition indicates key alterations in cell behavior.
The study highlights the role of m6A modification in inhibiting the effects of SRSF9 on cancer.
This research provides insights into the molecular mechanisms behind ovarian cancer progression and potential therapeutic targets.

Implication

Observational analysis shows SRSF9 enhances cancer cell growth and metastasis, suggesting m6A modification may hinder this process.

Abstract

Effect of SRSF9 knockdown on ovarian cancer cell growth, metastasis and epithelial-mesenchymal transition.

Discussion

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Cite This Study

Zuo et al. (2025) studied this question.

synapsesocial.com/papers/68f199bfde32064e504dcb91 https://doi.org/10.1158/0008-5472.30363288

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S6 from SRSF9 Forms Phase-Separated Condensates to Promote Ovarian Cancer Progression by Inducing RNA Alternative Splicing That Is Inhibited by m<sup>6</sup>A Modification2025
2Figure S9 from SRSF9 Forms Phase-Separated Condensates to Promote Ovarian Cancer Progression by Inducing RNA Alternative Splicing That Is Inhibited by m<sup>6</sup>A Modification2025
3Figure S1 from SRSF9 Forms Phase-Separated Condensates to Promote Ovarian Cancer Progression by Inducing RNA Alternative Splicing That Is Inhibited by m<sup>6</sup>A Modification2025
4Figure S7 from SRSF9 Forms Phase-Separated Condensates to Promote Ovarian Cancer Progression by Inducing RNA Alternative Splicing That Is Inhibited by m<sup>6</sup>A Modification2025
5Figure S10 from SRSF9 Forms Phase-Separated Condensates to Promote Ovarian Cancer Progression by Inducing RNA Alternative Splicing That Is Inhibited by m<sup>6</sup>A Modification2025