Table S1 from SRSF9 Forms Phase-Separated Condensates to Promote Ovarian Cancer Progression by Inducing RNA Alternative Splicing That Is Inhibited by m⁶A Modification

Xinzhao Zuo; Jie Xu; Dan Yang; Chenyue Yang; Xiaoyi Liu; Ningxuan Chen; Haocheng Wang; Xin Luo; Qingya Luo; Yuan Wang; Qinglv Wei; Yu Yang; Hongyan Zhao; Jing Xu; Wei Wang; Tao Liu; Ping Yi

doi:10.1158/0008-5472.30363267

October 15, 2025Open Access

Table S1 from SRSF9 Forms Phase-Separated Condensates to Promote Ovarian Cancer Progression by Inducing RNA Alternative Splicing That Is Inhibited by m⁶A Modification

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Key Points

SRSF9 involvement in RNA splicing promotes ovarian cancer progression through phase-separated condensates.
Key findings indicate that m6A modification effectively inhibits the RNA alternative splicing induced by SRSF9.
This analysis focuses on SRSF9's role in tumor biology and highlights potential therapeutic targets in cancer treatment.
The implications of this work point to the importance of RNA modifications in cancer progression and therapy.

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Implication

Observational analysis reveals RNA alternative splicing promotes ovarian cancer progression, suggesting m6A modification inhibition may provide therapeutic avenues.

Abstract

Sequences of shRNA oligos and antisense oligonucleotides used in the study.

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Cite This Study

Zuo et al. (2025) studied this question.

synapsesocial.com/papers/68f199c5de32064e504dcd48 https://doi.org/10.1158/0008-5472.30363267

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Table S1 from SRSF9 Forms Phase-Separated Condensates to Promote Ovarian Cancer Progression by Inducing RNA Alternative Splicing That Is Inhibited by m⁶A Modification

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

Table S1 from SRSF9 Forms Phase-Separated Condensates to Promote Ovarian Cancer Progression by Inducing RNA Alternative Splicing That Is Inhibited by m⁶A Modification

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

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