Population
Salt-fed F2 populations derived from crossing Dahl salt-sensitive and Lewis rats, and Dahl S and…
Comparison
Genetic analysis of the SA gene locus vs Comparison between different genetic crosses
Design
Preclinical
Authors
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Strain-specific SA locus effects in rat models caution against direct translation; leaves open its contribution to human hypertension.
The SA gene or a closely linked gene can contribute significantly to genetic hypertension depending on the genetic background.
Harris et al. (1993) studied this question.
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