Why the study?
Are ACE/DD, AGN/TT, and apoE/epsilon4 genotypes associated with cerebral infarction and cerebral hemorrhage in a Japanese population?
Population
Japanese patients with cerebral infarction and cerebral hemorrhage diagnosed by brain computed tomography…
Comparison
Presence of ACE/DD, AGN/TT, and apoE/epsilon4… vs Absence of these genotypes / control subjects
Design
Case-control
Authors
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ACE/DD with AGN/TT associated with higher cerebral infarction risk in Japanese; hypothesis-generating, requires prospective validation before clinical use.
Are ACE/DD, AGN/TT, and apoE/epsilon4 genotypes associated with cerebral infarction and cerebral hemorrhage in a Japanese population?
The ACE/DD genotype is associated with an increased risk of cerebral infarction, which is further enhanced by the presence of the AGN/TT genotype in a Japanese population.
Yozo Nakata (1997) studied this question.
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