Key result
Dextran infusion increases stroke volume by ~19% during severe exercise versus no dextran.
Authors
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Indicates preload reserve during severe exercise in dogs; leaves open translation to human athletes and clinical relevance.
Mean Difference: 5.4
p-value: p=<0.01
Horwitz et al. (1985) studied this question. Dextran infusion vs. Exercise without dextran was evaluated on Stroke volume during severe exercise (+5.4 ml or 19%, p=<0.01). Dextran infusion (14 ml/kg iv) increased stroke volume by 5.4 ml (19%) during severe exercise compared to exercise without dextran (P<0.01).
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